Both idiopathic tremor and Parkinson’s disease are diseases characterized by “tremor”. However, idiopathic tremor and Parkinson’s disease have different causes and pathologies. Although idiopathic tremor is different from Parkinson’s disease, both idiopathic tremor and Parkinson’s disease can be treated with disfiguring surgery and DBS. Idiopathic tremor, also known as primary tremor and benign tremor, is one of the most common adult tremor disorders, with a prevalence of about 0.4 to 5%, and the incidence increases with age.ET is considered a benign disease that does not reduce the patient’s life expectancy, and it is a movement disorder that manifests itself exclusively as a tremor, which is mainly characterized by action and postural tremor of the hands or head and is not accompanied by muscular stiffness or slowness of movement, among others. . In some patients, the tremor worsens during exercise, while in others it is initially associated with action tremor and rarely occurs at rest. It is aggravated by nervousness, emotional stress, hunger, and fatigue. All parts of the body can be affected, the affected parts are hands, followed by the head, throat muscles, lower limbs and chin, and rarely occurs in the trunk and tongue; the tremor usually starts from one side of the hands, and gradually extends to the whole upper limbs and contralateral upper limbs, and then up to the head and throat muscles, and is more pronounced on one side. The frequency is usually 4-12 Hz, and decreases with age, independent of the duration of the disease. It is intermittent at first, progressing to persistent, and generally progresses slowly. More than 50% of patients with ET have a positive family history, and the age of onset is characterized by a bimodal pattern: 20-29 and 60-69 years, with both sexes affected. Genetic studies of ET have shown that multiple causative loci have been localized in different families, but some scholars believe that ET develops from a combination of genetic and environmental factors. The disease generally progresses slowly, with most cases progressively affecting fine motor movements 5-10 years after onset. Pathological studies of this disease have not found any abnormal changes so far. The etiology and pathogenesis of the disease are not known, and may be related to abnormalities such as synchronized discharges in multiple motor units of the central or peripheral nervous system. A distinctive feature of idiopathic tremor is the significant inhibitory effect of small doses of alcohol, which is ethanol-specific but cannot be used as a routine treatment because of its tolerance, addictive properties, and some toxicity. The American Academy of Neurology (AAN) Quality Standards Subcommittee issued a protocol for the medical and surgical treatment of idiopathic tremor that recommends first-line medications of propranolol and pramipexole, second-line medications of alprazolam, atenolol, gabapentin, sotalol, and topiramate, and third-line medications of clonazepam, clozapine, nadolol, and nimodipine. For limb tremor that is ineffective with medication, if it causes serious impact on the patient’s daily life, surgical treatment, including thalamotomy and deep thalamic brain stimulation (DBS), is an option with strict indications.