Salmonella is an intestinal pathogen whose infection is often caused by unclean diet. Patients infected with Salmonella can lead to infectious gastroenteritis with severe diarrhea, vomiting, fever, malaise and other uncomfortable symptoms. At this time, patients should immediately go to the hospital for blood routine, blood biochemistry, vomiting and fecal examination, etc., in order to confirm the diagnosis, and isolation and treatment after diagnosis. After the diagnosis is confirmed, patients need to be treated with oral propantheline or subcutaneous injection of atropine and other drugs under the guidance of professional doctors to relieve vomiting and abdominal pain; due to persistent vomiting and excretion, when the patient’s body loses a lot of water, he/she needs to replenish fluids in time in order to avoid water and electrolyte disorders. If the patient’s symptoms are serious, need to use drugs to induce vomiting or gastric lavage and other means to remove the residual poison in the digestive tract, while the patient can also take diuretics, so that the toxins are discharged with the urine. As Salmonella is contagious, patients need to be isolated until they are cured, pay attention to the room’s open windows and ventilation, and disinfect the bed sheets, covers, clothing and other items used to prevent infection. The patient’s stomach and intestines are in a weak stage, should avoid eating greasy, cold and spicy food, so as not to stimulate the stomach and intestines and aggravate the discomfort symptoms. In addition, in daily life, patients should wash their hands with water and soap before meals and after defecation, and place raw and cooked food separately to minimize the possibility of salmonella infection.