Frequent panic attacks and shortness of breath are often considered cardiogenic factors, such as myocardial ischemia, arrhythmias, and cardiac insufficiency, and are commonly seen in patients with coronary artery disease. Coronary artery disease can include many types, including angina pectoris, myocardial infarction, asymptomatic myocardial ischemia, ischemic heart failure, and sudden death. Patients with coronary artery disease often present with symptoms related to chest pain, palpitations, and shortness of breath. Frequent panic attacks and shortness of breath also require the exclusion of endocrine-related disorders, such as hyperthyroidism, which have the potential to lead to hyperthyroid heart disease. In addition, electrolyte disorders can present with cardiac arrhythmias, such as tachyarrhythmia, leading to the development of symptoms such as dyspnea. In patients with pulmonary diseases, chronic obstructive pulmonary disease and chronic pulmonary heart disease, frequent panic attacks and shortness of breath can also occur.