Halo nevus type vitiligo in medicine refers to centrifugal acquired white spots, its cause may be related to immune system disorders, trauma and other factors, the patient’s skin pigmentation around the nevus will appear hypopigmented spots. Patients can take medication and physical therapy to improve their condition, and most patients have a better prognosis after standardized treatment. Centrifugal acquired leukoplakia is a kind of pigment loss disease, the cause of which is mostly related to immune system disorders, trauma, vitiligo and other factors, the patient’s skin will appear round or oval hypopigmented patches of varying sizes, and a white halo may appear around the nevus, which is uniform in color and will gradually increase in size. Patients can apply glucocorticoid drugs, such as Hasinide and Halomethasone, which can play an immunosuppressive role, can stop the spread of white spots, and may prompt part of the skin color to recover. In addition, patients with extensive lesions may also be able to combine the use of phototherapy (PUVA, NB-UVB) to irradiate the area, which can help improve skin symptoms. Most patients with centrifugal acquired leukoplakia have a better prognosis after standardized treatment, and patients should do a good job of sun protection, avoiding skin damage and maintaining a good state of mind. Patients are advised to go to regular hospitals and cooperate with doctors for standardized treatment.