Pre-eclampsia refers to a small amount of vaginal bleeding and/or pain in the lower abdomen at less than 28 weeks of gestation, the opening of the uterus is not open, the pregnancy is not expelled, and the size of the uterus matches the number of weeks of menopause; most miscarriages occur in early pregnancy and are called early-trimester miscarriages. 1. Etiology: There are many causes of pre-eclampsia miscarriage. The main causes are ① chromosomal abnormality of the parents, ② endocrine disorders and systemic diseases of the mother, such as hypothyroidism, luteal insufficiency, diabetes, hypertension, etc., ③ malformation and inflammation of reproductive organs, ④ bad habits, such as smoking, alcoholism, drug abuse, etc., ⑤ immune factors, such as blood type incompatibility, fetal antigens, etc., ⑥ excessive mental stimulation, ⑦ environmental factors, exposure to too many chemical substances, etc. 2.Clinical manifestations：A small amount of vaginal bleeding or bloody discharge, accompanied by (or) lower abdominal pain or low back pain after pregnancy. Depending on the amount of vaginal bleeding and the time the blood is in the vagina, the blood can be bright red or dark brown or even black. 3.Diagnosis: ①Clinical manifestations: early intrauterine pregnancy determined by ultrasound after menopause, vaginal bleeding and/or lower abdominal pain and low back pain within 28 weeks of pregnancy, without clinical symptoms of pregnancy discharge. ②Gynecological examination: If the pregnant woman is eager to keep the fetus, the examination can be suspended. If there is a lot of bleeding and abdominal pain, combined with blood-HCG results, gynecological examination should be performed gently to observe whether the uterine orifice is dilated, whether the amniotic sac is bulging, and whether there is pregnancy material blocking the uterine orifice. ③Auxiliary examination: ultrasound examination: according to the shape of the gestational sac, the presence or absence of fetal heart and fetal movement, determine whether the embryo or fetus is alive to guide the treatment. Blood-HCG and progesterone to monitor the prognosis and regression of miscarriage. 4. Treatment: The aim of treatment is to preserve the fetus. Whether or not a preterm miscarriage leads to inevitable miscarriage often depends on whether the embryo is abnormal. If the embryo is normal, after rest and treatment, the bleeding stops and the abdominal pain disappears pregnancy can continue. However, most miscarriages are caused by embryonic abnormalities, and the possibility of miscarriage is still high. ①General treatment: release the mind, bed rest, adequate nutrition, avoid stimulating factors that cause uterine contractions, such as sexual intercourse, constipation, diarrhea, repeated vaginal examinations, etc. ②Medication: according to the condition, small doses of sedatives can be given, and progesterone can be used to preserve the fetus if the luteal function is insufficient. It can also be combined with herbal medicine for fetal preservation. ③Pregnant women should go to the hospital as soon as possible if they find signs of preterm abortion such as vaginal bleeding. Do not delay the condition. Because there are many causes of preterm miscarriage, the treatment varies from person to person. If the cause cannot be addressed, the risk of inevitable miscarriage increases. 5. Precautions: ①Patients should rest in bed (except for urination and defecation) during the period of birth control, sexual intercourse is strictly prohibited, emotional stability should be maintained, and adequate nutrition should be supplemented. ② Pay attention to the amount and nature of vaginal bleeding: if the embryo is normal and the cause of miscarriage is eliminated after rest and and treatment, the bleeding will stop and the pregnancy can continue. If there is a lot of vaginal bleeding and/or significant abdominal pain, you should go to the hospital promptly. If there is tissue discharge (flesh-like tissue) from the vagina, prompt medical attention should be sought and the discharge should preferably be taken to a hospital with laboratory conditions for examination.