Patient: Description of the condition (onset, main symptoms, hospital visited, etc.): 30 years old without having children. HPV infection was found during pregnancy test. 2011.7.14 at Beijing Obstetrics and Gynecology Hospital: 3.4 points one and CINII and CINII-III involved in the gland. 1.2 slices occasionally very few CIN fragments incomplete. HPV result is high sub 31 52 Not yet I know you are an authority in this field, I would like to know whether this case should be done by lip knife or conization? I’d like to know whether to do a laparotomy or a cone? Zhao Xiaofeng: Your case still needs complete colposcopy results. The initial judgment of your condition is that the choice of LEEP or cold knife conization lies mainly with the doctor, some doctors are good at cold knife conization and some are good at LEEP, whether it is cold knife conization or LEEP knife as long as the excision range is reached, the treatment purpose can be achieved. Of course, regardless of the procedure, there will be a few people who will still have recurrence or reoccurrence. From the pathological point of view, the cold knife cone cut is more conducive to the determination of the cutting edge and facilitate the operation of the pathologist. From the point of view of fertility, the LEEP procedure should have less impact on the cervix and can maintain the normal structure of the cervix to a large extent. LEEP is also more favorable in terms of ease of operation, less bleeding and less cost. In our hospital, the LEEP procedure is basically done on an outpatient basis and does not require anesthesia.