A high C-reactive protein in children and a fever that usually lasts for several days are mainly related to the specific symptoms and treatment of the child, and cannot be generalized. C-reactive protein is an indicator of inflammation, but it is not specific and may be associated with acute or chronic inflammation or autoimmune reactions in the body. If the child only has elevated C-reactive protein and other laboratory indicators are not significantly abnormal, but there is fever, it is considered to be caused by bacterial or viral infection, usually for about 3 days, or there may be recurrent fever, which needs to be closely observed. However, if the child has elevated C-reactive protein, significantly higher white blood cell and neutrophil ratios, and a chest X-ray or CT showing a large area of lung infection, the situation is more serious and the fever may last for more than 10 days. Children with body temperature over 38.5℃ can apply antipyretic drugs; when the body temperature is below 38.5℃, physical cooling is the main concern, and cooling patches or warm water wipes can be applied. If the fever persists, parents should promptly take their children to the pediatric internal medicine department of a regular hospital for consultation.