Some patients with condyloma acuminatum will have pain, as well as foreign body sensation, itching and other symptoms; most patients do not have pain. Condyloma acuminatum is caused by human papilloma virus infection, a small number of patients do experience pain, as well as foreign body sensation, itching, discomfort during sexual intercourse, bleeding from the urethra, and abnormal urine flow. However, most patients with acromegaly have no obvious symptoms and no pain. It is recommended that patients with condyloma acuminatum should seek medical treatment in a timely manner. Patients can follow the doctor’s instructions to use onychomycosis cream, imiquimod cream, etc., and can also take physical therapy, such as freezing, laser therapy, electrocautery, etc.. The patient can also take surgical treatment to remove the skin lesions. The pain of warts varies from person to person, patients should go to the hospital in time, under the guidance of the doctor to take treatment measures.