A mole, also called a pigmented mole, is a benign growth of the skin. It can be said that almost everyone has more or less different moles, and it can grow in various parts of the skin mucosa all over the body, and moles may also grow on the hands. The sudden growth of moles on the hands depends on the location of the mole. If it is on the back of the hand and the lesion is relatively small, this condition usually does not require treatment. However, if it appears on the palm of the hand, because the palm of the hand has to repeatedly hold things, or is exposed to some hot and cold stimuli, this situation is not conducive to the long-term existence of the mole. In this case, it is recommended to remove the mole surgically, especially if it is relatively large or if it is painful, itchy, has deepened color, or has inflammatory reaction.