For the drug treatment of frequent chest tightness, shortness of breath, dyspnea and weakness of limbs, the first thing to do is to clarify the etiology of these clinical symptoms. 1. For patients with hypothyroidism, the diagnosis can be clarified after laboratory tests of thyroid function, and their treatment requires active supplementation of thyroid hormones to improve the symptoms. 2. If the above symptoms are caused by cardiac insufficiency, patients should actively use diuretics and other drugs for heart failure under the guidance of the doctor to relieve the symptoms of fatigue, chest tightness and shortness of breath. 3. Anxiety patients may also suffer from chest tightness, shortness of breath, dyspnea and weakness of limbs, which may be significantly improved or even completely relieved by the use of anti-anxiety drugs. 4. For the symptoms of frequent chest tightness, shortness of breath, dyspnea and weakness of limbs caused by hypokalemia, patients can take potassium chloride extended-release tablets to relieve the symptoms. Therefore, patients should consult hospitals before using medication to find out the cause of the disease and then give targeted treatment.