Pearl rash generally refers to penile pearl rash, and there are many differences between the symptoms of warts, such as different etiology, different parts of the onset, different characteristics of skin lesions, etc.,. 1. different etiology: penis pearl rash etiology is unknown, may and circumcision, local friction stimulation and other factors; warts is caused by human papilloma virus infection caused by sexually transmitted diseases. 2. the onset of different parts: the penis pearl rash occurred in the glans coronal groove edge, ring-shaped distribution led to a circle of small pimples the size of a grain of rice; warts will occur in the foreskin, the foreskin tie, the coronal groove, the body of the penis, perineum, perianal and other parts of the anus. 3. lesion characteristics are different: penis pearl rash size of rice grains or fish seeds, size transparent, translucent surface smooth, slightly hard texture; warts lesions characterized by cauliflower-like, papillary organisms, soft texture, sharp tip, the surface is easy to vesiculation, there is oozing and infiltration, breakthroughs. The penis pearl rash and warts can generally be distinguished from the symptoms and laboratory tests, it is recommended that the patient to go to the hospital, under the guidance of the doctor for diagnosis and treatment.