In outpatient clinics, we often encounter patients with colds who ask for antibiotics, saying that they are good for colds. Some people are used to having them at home and often ask their doctors to dispense more. The common cold is the most common acute respiratory tract infection. According to statistics, adults suffer from the common cold 2-6 times a year, and children on average 6-8 times, and everyone inevitably has to deal with cold medicine. At present, it seems that there are no antiviral drugs for cold treatment at home and abroad. Domestic “2012 common cold diagnosis and treatment guidelines” clearly states that the use of antibacterial drugs is not recommended to treat the common cold, and the prevention of bacterial infection with antibacterial drugs is ineffective. There is no need to treat the common cold with antiviral drugs. So for the common cold, I usually advise patients to drink more water and rest. Or use simple herbs or western medicine to relieve some discomfort. But if the symptoms persist for 7-10 days without improvement, or if the patient develops fever, increased white blood cells, and increased C-reactive protein, then only then bacterial infection is considered and can be treated with antibiotics. There are three types of bacteria that appear most frequently in upper whistle infections: Streptococcus pneumoniae, Haemophilus influenzae, and Cataplasma. All are basically in the antibacterial spectrum of penicillin and cephalosporin antibiotics. If patients are allergic to these two types of drugs, they can use erythromycin. In addition, Chinese medicine is also very effective for colds and rarely produces drug resistance.