Recently, our pain department successfully performed radiofrequency surgery on the trigeminal hemimelia for a patient with trigeminal neuralgia. The patient was a 60-year-old male with trigeminal neuralgia for 28 years. He had been taking carbamazepine and pain relief tablets for a long time, but now he had developed drug resistance and his pain was getting worse, seriously affecting his daily life. The patient has been treated in many hospitals, but has failed to improve. Recently, he came to our pain clinic and was admitted to our hospital. After analyzing the patient’s medical history, physical examination and auxiliary examination results, all physicians in the pain department concluded that the patient’s diagnosis of trigeminal neuralgia was clear, and the patient’s long duration of illness and severe pain seriously affected his normal life and physical condition. The patient and his family had a strong desire for surgery and understood the possible risks of surgery. The operation was presided over by Director Huang Dong, with Deputy Director Liao Qin as the first assistant. The surgery was performed with the patient fully awake and the procedure was very smooth. The patient recovered well with complete pain relief and no complications. The most important clinical manifestation of trigeminal neuralgia is pain. This pain, which is very intense, is often unbearable. During the pain attack, the patient often suddenly stops talking and eating, frowns and clenches his teeth, opens his mouth to cover his eyes, or rubs his face with the palm of his hand, resulting in abnormal thickening and roughness of the skin, loss of eyebrows, and extremely painful expressions, often accompanied by paroxysmal spasms of facial muscles and masticatory muscles (i.e. “painful twitching”), combined with membrane congestion, tearing and salivation. Because trigeminal neuralgia is a more persistent neuropathic pain, the efficacy of commonly used analgesic drugs varies greatly and the effect of drug treatment decreases with the progress of the disease, and it is extremely rare to be cured clinically. Our department has introduced the latest American radiofrequency treatment system, which has an immediate effect on the treatment of intractable neuropathic pain.