A folic acid metabolism test is necessary. This test is usually performed during the couple’s preparation for pregnancy, with blood drawn in the morning on an empty stomach, to check whether the woman’s body contains enough folic acid to support fetal growth and development. Folic acid is a water-soluble vitamin necessary for cell growth and development. Over 50% of newborns with neural tube defects are associated with folic acid deficiency and supplementation can significantly reduce the incidence, so a folic acid metabolism test is necessary to prevent fetal abnormalities by supplementing with folic acid if there are abnormalities. The risk of folic acid metabolism is divided into 3 types: low risk refers to a woman’s normal ability to absorb and metabolize folic acid; medium risk refers to a woman’s abnormal ability to absorb and metabolize folic acid, which usually does not lead to fetal malformation; high risk refers to a woman’s possible disorder of folic acid metabolism and the need to take folic acid appropriately. Folic acid is widely found in eggs, animal offal and fruits and vegetables, such as eggs, pork liver, grapes and spinach, etc. It can be supplemented by daily diet, and can also be supplemented by oral folic acid under the guidance of a doctor. Be careful not to take medication without permission to avoid adverse effects from overdose. During the preparation period, you should do pre-conception check-ups, manage your emotions and quit bad habits such as smoking, drinking and staying up late. In addition to folic acid, attention should be paid to the content of trace elements such as iron, calcium and iodine in the body. It is recommended that women consume animal offal, lean meat, spinach and fruits appropriately during pregnancy preparation to promote the absorption of trace elements such as iron and calcium.