Axillary odor, also known as “fox odor”, is a common genetic skin disease. It is common in young adults, especially in women; symptoms vary in severity and can be reduced or disappear in old age; it increases in summer when sweating increases. Axillary odor does not affect human health, but in today’s frequent interpersonal interactions can easily bring great psychological pressure and low self-esteem, affecting the patient’s work, study and life. Axillary odor is caused by the decomposition of organic matter in the secretions of the top sweat glands by epidermal bacteria on the surface of the armpit to produce unsaturated fatty acids. The skin’s bacterial decomposition of odor does not explain the genetic characteristics of axillary odor and the characteristics of youth onset, and simple bactericidal treatment cannot cure axillary odor. The principle of botulinum toxin for armpit odor: when injecting botulinum toxin type A into the appropriate part of the armpit, botulinum toxin will inhibit the release of acetylcholine from the sympathetic postganglionic fibers that innervate the sweat glands, thus leading to the gradual atrophy of the sweat glands in the armpit area and the gradual reduction of sweat secretion, thus achieving the purpose of removing armpit odor. The advantages of Botox for armpit odor: First, its treatment effect is obvious. Secondly, because it does not require surgery, it can avoid all the complications that come with surgical treatment. The disadvantages of Botox for armpit odor: Botox for armpit odor is not permanent, some people injected once can last about six months – 1 year, need to repeat the injection. Despite its shortcomings, Botox for armpit odor has obvious advantages and is a reliable and trustworthy treatment method.