Axillary odor, one of the common skin diseases, especially in summer, because of the hot weather and sweating, the odor will seem more intense than in other seasons, where the unpleasant smell to walk to where, people around often avoid it, seriously affect the normal social activities, and even bring psychological barriers to patients. Where does armpit odor come from? Some patients with axillary odor have a clear family history, and the incidence of the child is higher if the parents have this problem. Therefore, it is possible, but not absolute, that armpit odor is related to genetic factors. Why does it smell so bad? This is mainly because the sweat excreted by the sweat glands (also called parietal glands) in the armpits, vulva and corners of the mouth of patients with axillary odor is higher in fatty acids, light yellow and thicker than that of ordinary people. When the fatty acid reaches a certain concentration, it is decomposed by bacteria (mainly staphylococcus) on the surface of the skin to produce unsaturated fatty acids and emit an odor. Patients with armpit odor are deeply distressed due to body odor, and often use topical antiperspirant, perfume, flower lotion, etc. to reduce odor, but the effect is often poor. There are many ways to treat axillary odor, but in general, destroying the acromegaly is considered to be the key to the cure of axillary odor. The parietal sweat glands usually develop rapidly during puberty, and secretion gradually reaches its peak, so the best time for patients to be treated is after puberty, otherwise they are prone to recurrence. Axillary odor is a distressing social problem that can seriously affect the quality of life of patients. Invasive surgical treatment can permanently remove the odor. Treatment options include surgical excision of the axillary skin and the subcutaneous sweat glands underneath, small incision subcutaneous sweat trimming, minimally invasive subcutaneous sweat scraping, fat aspiration, and more. However, patients suffer from early postoperative effects on upper limb movement, long recovery times and the possibility of significant scarring with some methods. Intradermal injection of botulinum toxin type A is an effective treatment for axillary hyperhidrosis. Its chemical denervation action blocks the cholinergic nerve endings that innervate the small and large sweat glands, inhibiting sweat secretion. Botulinum toxin type A has been shown to be effective only in the treatment of certain types of axillary odor. Therefore, it is necessary to identify the indications for botulinum toxin. It was found that botulinum toxin reduces odor mainly by inhibiting the secretion of small and large sweat glands, but not macrohidrosis. After treatment, it was found that sweating was significantly reduced, followed by the elimination of odor. Patients with a strong relationship between sweating and odor prior to treatment were able to achieve more satisfactory results.