Trigeminal neuralgia treatment is a collection of 1, drug treatment: (1) carbamazepine: reduce the excitability of cells, may also reduce the synaptic transmission of central nerve about, is the drug of choice for trigeminal neuralgia and lingual neuralgia drug treatment, also used as a long-term preventive drug after the relief of trigeminal neuralgia. At present, there are two types of domestic products: imported (boxed) and domestic (bottle), and the domestic type is generally available in small doses of 100mg tablets, taken orally 2-3 times/d, and gradually increased to 200mg, taken orally 3-4 times/d. There may be toxic side effects such as drowsiness, nausea, vomiting, dizziness and drug rash, which are generally not serious and can disappear on their own after dose reduction or discontinuation. For patients with greater side effects and poor pain control, some oxcarbazepine drugs can be selectively taken orally, which as an upgraded version of carbamazepine, have fewer side effects but are slightly more expensive. (2) Phenytoin sodium: 100-200mg, 2-3 times/d. Daily dose should not exceed 600mg, side effects include gingival hyperplasia, ataxia and leukopenia. (3) Vitamin B drugs: vitamin B1, B6, 10-20mg each, 3 times/d orally, vitamin B12, 100-500μg intramuscularly or 500μg orally. (4) Vasodilators: scopolamine (654-2) 10mg, 2 times/d intramuscularly or 5-10mg orally, 3 times/d, or nicotinamide 100mg orally, 2.Nerve block or closure therapy When drug therapy is ineffective or has adverse reactions, and the pain is severe, nerve trunk or ganglion block therapy is feasible. In the past, anhydrous alcohol was often used, but in recent years, glycerin has been injected more often. The injection site is the trigeminal nerve hemimelia or peripheral nerve trunk. The pain is relieved by the destruction of sensory nerves. The pain-relieving effect can last for months or years, but it can also recur. 3.Radiofrequency electrocoagulation therapy Under the supervision and guidance of image guidance or neuronavigator, radiofrequency electrocoagulation needle is inserted percutaneously into the semilunar ganglion and heated to 65~75℃ for 1min, which can selectively destroy the nociceptive fibers of trigeminal nerve, which can selectively destroy the nociceptive fibers of trigeminal nerve, and the recent efficacy can be more than 95%, but it is easy to recur. It is suitable for the elderly and those who suffer from systemic diseases and cannot be operated. 4, stereotactic gamma knife radiation therapy “Gamma knife” called “knife”, but in fact is not a real scalpel, it is a hemispherical helmet covered with direct aligner, the helmet can shoot 201 cobalt 60 high dose ion rays – gamma rays . It is precisely located in a certain area through modern imaging technology such as CT and MRI, which we call “target point”. Its positioning is extremely accurate, the error is often less than 0.5 mm; each gamma ray dose gradient is very large, almost no damage to the tissue. The planned gamma rays of a certain dose are concentrated on the pre-selected target site in the body, destroying the tissue in the site in a one-time, lethal manner to achieve the effect of surgical excision or destruction. It is named because it functions like a scalpel and has the advantages of being non-invasive, not requiring general anesthesia, no incision, no bleeding and no infection. However, its disadvantage in treating trigeminal neuralgia is its slow onset of action, mostly 3-6 months after surgery, during which the patient still has to suffer from pain. The postoperative adverse effects are the same as radiofrequency destruction treatment. 5.Surgical treatment Surgical procedures include: microvascular decompression, selective trigeminal nerve sensory root amputation, which is also the best treatment method recognized by experts at home and abroad. It is the only method to effectively and completely cure trigeminal neuralgia. The pathogenesis of trigeminal neuralgia is caused by vascular compression. The literature shows that 85% of patients with trigeminal neuralgia have vascular compression of the trigeminal nerve near the cerebral bridge. It is most commonly an artery and rarely a vein. In the case of branch 2 and 3 pain, compression of the superior cerebellar artery on the cephalad superior part of the trigeminal nerve is usually found, and in the case of branch 1 pain, it is usually the anterior inferior cerebellar artery that compresses the caudal inferior part of the trigeminal nerve. The purpose of the surgery is to completely separate the compressed nerve from the surrounding blood vessels, to “reline” the blood vessels, or to place a Teflon insulating pad between the nerve and the blood vessels to isolate the direct contact between the blood vessels and the nerve, so that the compressed nerve can be released and no more pain can occur. Through this procedure, the patient’s pain can be completely eliminated without side effects such as facial numbness and abnormal sensation, thus achieving a minimally invasive, safe and efficient treatment.