Usually amoxicillin itself does not affect vaccination. If there is no disease and only amoxicillin is taken by mistake, it usually does not affect vaccination and can be given 1-3 hours after taking the drug; however, if amoxicillin is taken due to the presence of infection or even the presence of fever, etc., immediate vaccination is not recommended and can be given after recovery from the disease or after the acute period has passed. Amoxicillin belongs to the class of antibiotics that can inhibit or kill bacteria and help treat bacterial infectious diseases, while vaccines work by inducing an immune response, so they generally do not affect the effectiveness of the vaccine, so amoxicillin itself does not affect vaccination. If you are concerned that taking amoxicillin will have an effect on the efficacy of the vaccine, you can take some time between vaccinations. The half-life of amoxicillin is about 1 hour, so you can take the vaccination after 1-3 hours and inform the vaccinating doctor that you have taken amoxicillin before the vaccination. If you are taking amoxicillin due to a bacterial infection and are still in the acute phase of inflammation before preparing for vaccination, such as the presence of fever, diarrhea, abdominal pain, cough, sputum, and localized pain, it is generally recommended to postpone vaccination. Because vaccines activate the body’s immune system to produce antibodies to defend against related diseases, when inflammatory infections occur in the body, the immune system needs to fight against the infection with all its strength, and vaccination at this time may increase the burden on the immune system, which is not conducive to antibody production and recovery from diseases, and also increases the probability of adverse reactions to vaccines. Therefore, vaccination is not recommended at this time, and it is recommended to wait for the recovery of the disease before vaccination. Therefore, how long it takes to get vaccinated after taking amoxicillin depends on how long it takes to recover from the disease. Generally, as long as the disease recovers and the doctor confirms that there are no other contraindications, you can get vaccinated.