Scrotal pain may be diseases: first, scrotal skin cellulitis, the scrotal skin is routinely in a folded state, which may harbor a large number of bacteria, such as local inflammation of the hair follicle or local infection, can appear subcutaneous cellulitis. At this time, there may be redness and pain at the site of the lesion, and local edema and redness can be seen on physical examination. It is recommended that anti-infective drugs be administered, and cephalosporin antibiotics can be used for treatment, such as cefixime capsules twice a day or intravenous infusion of antibiotics for treatment. Secondly, scrotal pain may be the pain of the appendages, such as the testicles or epididymis. At this time, there is no redness or swelling of the skin, no abnormal bulging masses, but painful or painful nodules can be touched by hand to the testicles, and inflammation of the testicles or epididymis is mostly considered. If infection does exist, intravenous antibiotic infusion is needed for treatment, and a light, easily digestible diet and alcohol are prohibited during treatment. Cefoxitin 2g twice a day or cefuroxime sodium 1.5g twice a day can be used as antibiotics. Thirdly, acute torsion of the testicle, acute scrotal pain can occur when torsion, the testicle position is lifted and fixed when touched by hand, not the natural state of movement, the pain increases when touched by hand, this situation is a more acute situation, it is recommended to immediately seek medical attention for scrotal ultrasound examination. If there is testicular torsion, immediate surgery is needed to reset the testicle.