Department of Foot and Ankle Surgery, Beijing Tongren Hospital, Capital Medical University Aims of the study: to understand the clinical outcomes of patients who still had persistent pain in the front of the outer ankle more than 3 months after ankle sprain after treatment with foot pads. MATERIALS AND METHODS: From January 2014 to March 2015, 21 patients, 5 males and 16 females, aged 14-35 years, who still had persistent pain in the front of the outer ankle after ankle sprain for 3 to 9 months were admitted to the outpatient clinic. Among them, 13 cases were patients with ankle sprain without regular treatment and fixed rest. Nine cases were fixed by brace or cast after injury, among which four cases were not fixed strictly according to physicians’ requirements. All patients (those with positive ankle drawer tests) received foot pads for 6 weeks. AOFAS scores were investigated before use, after 1 week of use and after 6 weeks of use. Statistical methods were analyzed using ANOVA. 4 cases were lost to follow-up. RESULTS: The mean AOFAS score was 74.41±12.309 before treatment, 88.12±8.108 during treatment, and 89.53±8.501 after treatment. statistical results were statistically significant p<0.00 between pre-treatment and treatment, and between pre-treatment and post-treatment groups. p=0.262 was not statistically significant between the comparison between treatment and post-treatment groups. CONCLUSION: Foot pads have a significant therapeutic effect on chronic anterior talofibular ligament injury.