The anterior cruciate ligament (ACL) connects the tibia to the femur and is an important structure in maintaining the stability of the knee joint. In addition to its role as a bond, the sensory nerve endings in the ligament also play a role in maintaining knee stability through a proprioceptive feedback mechanism, and a ruptured ACL not only leads to knee instability, which affects motor function, but also aggravates joint damage by secondary injury to major intra-articular structures. Ten years after ACL rupture, the incidence of meniscal damage increases to more than 90% and the incidence of articular cartilage damage increases to 80%, leading to secondary traumatic arthritis and, in severe cases, joint replacement surgery. Therefore, ACL reconstruction is necessary in order to keep intra-articular damage from further deterioration.