The best way to treat jaundice is to target the cause of the jaundice and to use bilirubin-lowering medications. The main causes of jaundice are obstructive jaundice, hepatocellular jaundice, hemolytic jaundice, and congenital non-hemolytic jaundice. If obstructive jaundice is present, the cause of bile duct obstruction should be determined first, such as bile duct cancer, stones, cholangitis, parasitosis, etc. Therefore, anti-infection and stone extraction should be considered, and if necessary, surgical treatment can be performed to drain out the bile inside, thus playing a role in reducing the pressure in the bile duct; if it is caused by a tumor, surgical removal should be considered. For hepatocellular jaundice, treatment should be directed at the cause of abnormal liver cell function. Viral hepatitis, cirrhosis, sepsis, etc. are all causes of hepatocellular jaundice, and drugs that damage the liver should be used with caution, and the diet should also reduce protein intake, etc. These can all play a role in reducing the jaundice index. If the jaundice is caused by hemolytic jaundice, treatment should be directed at hemolysis and active treatment of hematologic diseases. For neonatal jaundice, attention should be paid to whether the jaundice is physiological or pathological. Physiological jaundice can be observed first, and if the neonatal jaundice is pathological, treatment for the cause of the neonatal pathological jaundice should be carried out. Therefore, the treatment of jaundice should vary from disease to disease, and the treatment for the cause is the most critical.