Smoking lips purple may be due to long-term smoking caused by coronary heart disease, chronic obstructive pulmonary disease and other reasons for the application of nitroglycerin, salbutamol and other drugs. 1. Coronary heart disease: long-term smoking is a risk factor for coronary heart disease, when smoking induced coronary heart disease, the heart can not pump enough blood, resulting in hypoxia manifested as purple lips, can be sublingual nitroglycerin relief. 2. Chronic Obstructive Pulmonary Disease (COPD): Smoking is the most common cause of chronic obstructive pulmonary disease (COPD). When smoking, nicotine and other substances in tobacco stimulate the lung tissues, leading to oxygen deprivation, which is manifested as purple lips. Available bronchodilators such as salbutamol and other drugs. The situation of purple lips after smoking, should be timely to the hospital, improve the relevant examination to clarify the cause of the disease, under the guidance of the doctor symptomatic treatment, avoid unauthorized use of drugs or treatment. Smoking is harmful to health and should be quit as soon as possible.