Imiquimod cream is an immunomodulator for the treatment of external genital and perianal warts in adults, and is effective against flat warts and common warts. The causative agent of warts is human papillomavirus (HPV), which is a benign superfluous organism caused by infection of human skin mucosa. Wash your hands before and after using Imiquimod cream to prevent secondary bacterial infections. The medication can be applied evenly to the affected area before going to bed, massage gently until the medication is completely absorbed, and keep it for 6-10 hours, then wash off the medication from the affected area with water and neutral soap, but avoid bathing during the medication period to prevent weakening its effect. Patients should follow their doctor’s instructions and use the cream continuously at the prescribed frequency to maximize its effectiveness, not to increase or decrease the dosage until the warts are completely eliminated. Imiquimod cream can stimulate the body to produce an immune response against HPV, reducing or eliminating HPV to treat the infection and reduce recurrence. If the patient feels general discomfort or experiences significant local skin reactions, including more pronounced edema, pain, itching, or even erosion, the medication should be discontinued and medical attention should be sought promptly. In addition, most common warts can disappear on their own. If warts continue to grow or are uncomfortable, they can be treated with topical or internal medications. In addition to Imiquimod cream, other topical medications can be chosen depending on the situation. For example, if you have flat warts, you can choose vitamin A acid cream, as well as fluorouracil ointment, but use with caution on the face because fluorouracil ointment can leave pigmentation.