In the clinic, we are often asked by the mothers of babies whether our children will be poisoned if they take vitamin D (400 IU) regularly. So today we will talk about what kind of measurement can cause vitamin D poisoning, the performance of vitamin D poisoning and how to deal with it? Generally, oral treatment of vitamin D is safe because the body has a feedback mechanism that can regulate itself, but misuse of excessive vitamin D, long-term use of large doses of vitamin D or those sensitive to vitamin D can lead to poisoning. It is generally believed that poisoning can occur in normal children who take 20,000 to 50,000 units or 2,000 units/kg/day for several weeks or months. What are the signs of vitamin D toxicity? The earliest symptoms are anorexia, followed by weight loss, depression, low-grade fever, nausea, vomiting, stubborn constipation, drowsiness, indifferent expression, and headache in older children. How is vitamin D toxicity treated? Immediately stop using vitamin D and deal with hypercalcemia, restrict calcium intake, use tachyphylaxis 0.5~lmg/kg/time intravenous push. Lower blood calcium through diuresis, repeat if necessary; pay attention to water and electrolyte balance.