Chondromalacia patellae is a condition in which the patellofemoral articular surface of the knee joint rubs against the femoral articular surface in the process of contact, specifically due to wear and degeneration of the cartilage of the patellofemoral articular surface. There is no strict sense that the disease can last for several years, but pain should be actively treated systematically. Pay attention to the maintenance of daily life, no recurrence of symptoms for a long time, there can be no problem at all. However, if the disease is not treated systematically and the pain is not dealt with, it is possible that the cartilage degeneration will become more and more serious within 3-5 years, and the cartilage degeneration has reached its worst condition, and only joint surface replacement surgery can be performed, because there is no way to regenerate the cartilage degeneration and metamorphosis.