Quinolones and tetracyclines in the treatment of Helicobacter pylori have the potential to affect sleep, and insomnia can be regulated by diet, rest and relaxation, and medication after taking Helicobacter pylori medication. 1. Diet: In the process of treatment, in order to avoid affecting the effectiveness of the drug and sleep treatment, should avoid eating spicy stimulating food, can drink some milk before going to bed. 2. Work and rest: should be regular work and rest, try to go to bed before 11 o’clock, avoid drinking stimulating beverages before going to bed, such as strong tea, coffee, etc., appropriate foot soak helps to relieve fatigue and help sleep, proper exercise during the day, do not sit and lie down for a long time. 3. Drugs: If insomnia seriously affects your life, you should take drugs under the guidance of a doctor, such as oral solution of tranquilizer and brain tonic, oral solution of jujube nut, etc., and western medicine can choose diazepam, eszopiclone, etc.. Insomnia patients should not blindly use their own medication, in the use of drugs to follow the doctor’s instructions in accordance with the dose.