1, indications A. Age > 3 years; B. Secondary foramen ovale septal defect diameter ≥ 5 mm, with increased right heart volume load, ≤ 36 mm left-to-right shunt atrial septal defect; C. Edge of the defect to the coronary sinus, superior and inferior vena cava and pulmonary veins distance ≥ 5 mm, to the atrioventricular valve ≥ 7 mm; D. The diameter of the septum is greater than the diameter of the selected blocking parachute; E. Not combined must be surgical E. Other cardiac malformations that must be combined with surgery. 2, relative indications A. age <3 years, but with increased right heart load; B. the atrial septal defect stump is absent or insufficient at the anterior edge, but the other edges are good; C. the stump around the defect is less than 5mm; D. with pulmonary hypertension, but QP/QS ≥ 1.5, arterial oxygen saturation ≥ 92%, can be blocked. 3, contraindications A. primary orifice type atrial septal defect and pulmonary venous sinus type atrial septal defect; B. infective endocarditis and hemorrhagic disease; C. thrombus exists at the placement of the blocker and venous thrombosis at the catheter insertion; D. severe pulmonary hypertension leading to right-to-left shunt; E. serious myocardial disease and valvular disease unrelated to atrial septal defect; F. infectious disease within the last month or infectious G. Hemorrhagic diseases and untreated gastric and duodenal ulcers; Atrial diaphragm defect is one of the most commonly used interventional disorders, and nearly 10,000 people are treated with atrial septal occlusion each year at a cost of 26,000.