Trigeminal neuralgia is typically characterized by severe paroxysmal pain in the area innervated by the trigeminal nerve in the face. The pain lasts for a few seconds or minutes and is unbearable, so it is known as the “number one pain in the world”. What are the methods to treat trigeminal neuralgia? 1.Medication: oral carbamazepine, gabapentin, oxcarbazepine and other drugs can be taken to control pain attacks; 2.Minimally invasive interventional treatment: trigeminal nerve hemimelia destruction, including chemical destruction and radiofrequency thermal coagulation technology. Chemical destruction is to use a nerve block needle to puncture into the trigeminal nerve hemimelia and inject drugs to destroy the responsible nerve; radiofrequency thermocoagulation is to place a very thin radiofrequency needle into the trigeminal nerve hemimelia, and the tip of the needle is heated to 70~80℃ to cause a slight denaturation of the proteins in the hemimelia, blocking the transmission of pain signals, this method is precisely positioned, less invasive and less expensive; 3, open surgery: that is microvascular decompression is to reduce the compression of blood vessels on the trigeminal nerve root by craniotomy. Which patients are suitable to choose minimally invasive interventional treatment? 1.Primary trigeminal neuralgia, standardized oral carbamazepine, pain cannot be relieved, seriously affecting the quality of life; 2.Obvious adverse drug reactions to carbamazepine and other drugs; 3.Patients who are too old and weak to tolerate and unwilling to accept craniotomy treatment; 4.Patients who relapse after craniotomy for trigeminal nerve vascular decompression; 5.Patients whose pain is not eliminated or reduced due to unsatisfactory effect of gamma knife treatment; 6.Patients whose pain is not eliminated or reduced due to tumor Trigeminal neuralgia caused by tumors, the pain of gamma knife or surgical treatment has not improved. What is the effect of minimally invasive interventional treatment for trigeminal neuralgia? At present, due to the precise positioning under the guidance of CT, C-arm and other imaging equipment, supplemented by neurophysiological monitoring, the interventional treatment is very precise and avoids damage to other nerve tissues. With the advantages of precise efficacy, small trauma and few complications, it has been widely used in clinical practice. Will half of the face lose consciousness after minimally invasive intervention? After minimally invasive intervention, the sensation of half of the face will still exist, but the sense of touch will be somewhat dull, and there will be numbness in the original painful area, which will gradually decrease with time. Compared to the original severe pain, patients usually feel that this numbness is nothing compared to the original pain. Most of the patients’ pain disappears after the procedure, but a few patients need 7 to 10 days for the pain to disappear. Therefore, it is important not to be too anxious after receiving the intervention. It should be noted that patients who have been using carbamazepine in large quantities for a long time should not stop the drug suddenly to avoid withdrawal symptoms, irritability, panic, dizziness, and even severe nausea and vomiting. The dosage should be gradually reduced after the procedure, aiming to stop the drug within a few days. In addition, patients after treatment should avoid eating strong stimulating foods, such as chili peppers and wine, and also avoid eating foods that are too cold, too hot, or with thorns to avoid adverse stimulation and damage to the nerves or oral mucosa.