The causes of premature ejaculation can be broadly categorized into two main groups: psychogenic and biogenic, and the treatment of premature ejaculation includes a variety of therapeutic means such as psychosexual therapy and drug therapy. 1. Etiology: (1) Psychogenic: anxiety, early sexual experience, low frequency of sexual intercourse, poor neural control, and so on. (2) Biogenic: existence of susceptible genotypes, 5-HT receptor dysfunction, endocrine diseases such as hyperthyroidism, drug abuse or in the withdrawal stage, ejaculatory reflex over-excitement, high level of sexual arousal, and so on. 2.Treatment: (1) Psychosexual therapy: all patients treated for premature ejaculation should receive basic psychosexual counseling or education. (2) Drug therapy: commonly used drugs include local anesthetic drugs (lidocaine, etc.), pentazocine reuptake inhibitors (dapoxetine, etc.) and other drugs. To summarize, for patients with premature ejaculation, they should go to the relevant departments of regular hospitals and be treated under the guidance of professional physicians, so as not to delay the condition and cause adverse consequences.