Moles are categorized as intradermal nevus, mixed nevus and junctional nevus, among which mixed nevus and junctional nevus have the possibility of malignant changes. The buttocks are easy to friction parts, in order to avoid long-term stimulation leading to malignant changes, it is still recommended to remove. Moles are medically known as nevus or melanocytic nevi, which are skin manifestations caused by an increase in melanocytes in the epidermis and dermis. If there is a very dark mole, left-right asymmetry, uneven or irregular edges, uneven pigmentation, unclear boundaries, rapid growth of the mole, etc., it is recommended that it be removed in a timely manner. If the buttock nevus does not have the above mentioned problems and does not affect normal life, it does not need special treatment and only requires attention and observation. If the mole on the buttock enlarges or itches on the surface, you should consult a doctor in time, follow the doctor’s instruction for further examination, and carry out targeted treatment or therapy under the doctor’s guidance.