Verrucous epidermal nevi (VEN), also known as linear verrucous epidermal nevi or linear epidermal nevi, are caused by epidermal abnormalities in the development of the epidermis due to overdevelopment of epidermal cells. Lesion characteristics: limited and systemic lesions located on the scalp: skin-colored or brown warty keratotic plaques with rough surface keratinization, may be accompanied by a little scaling; located on the face and neck, one side of the upper or lower limbs: brown papules arranged in sheet or band clusters, epidermis papilloma-like, a few brown warty keratotic plaques; located on the trunk: transverse or swirling or along the Blasehko line warty epidermal nevi (verrucousepidermalnevi, VEN), also known as linear verrucous epidermal nevus or linear epidermal nevus, is caused by epidermal cell overdevelopment causing epidermal restrictive developmental abnormalities. It is a brown wart-like keratotic plaque in the column. The inflammatory type is often itchy and intense, and the lesions are erythema, papules, and plaques arranged in a linear pattern, often with scales and crusts. Verrucous epidermal nevus (VEN), also known as linear verrucous epidermal nevus or linear epidermal nevus, is caused by epidermal cell overdevelopment resulting in epidermal restrictive developmental abnormalities. Clinically, due to the specific morphology of the lesions, the disease is generally easy to diagnose, but nearly one-third of patients have been misdiagnosed with a variety of other diseases. Limited VEN or ILVEN with lesions on the extremities is often misdiagnosed as linear lichen planus and linear moss, and limited VEN with lesions on the scalp is often misdiagnosed as sebaceous nevus, but it is not difficult to differentiate from these diseases by histopathological examination. Treatment for this disease is varied and includes topical retinoic acid, 5-fluorouracil or glucocorticoids alone, oral Avelox with topical 5-fluorouracil, tazarotene and halometasone, surgery, liquid nitrogen freezing, CO2:laser, and Er-YAG laser treatment. Topical medications are less effective and have a high recurrence rate after discontinuation. Oral Avelox with topical 5-fluorouracil, tazarotene and halomethasone is simple and easy to use, does not leave scarring, and is effective for pan-emergent lesions. Surgical treatment is effective, but leaves scarring and is only suitable for small lesions. Liquid nitrogen freezing is low-priced, easy to operate, and has good aesthetic effects, and is suitable for treating this disease, and has the best effect on small single lesions oral o. Continuous wavelength CO2: laser treatment is easy to operate and effective, but has a moderate recurrence rate.