As a common disease in the internal medicine system, the diagnosis of pulmonary hypertension has been a clinical challenge. Although the right heart float catheter is the gold standard for the diagnosis of pulmonary circulatory hypertension, its invasive nature and the development of complications have limited its widespread use. Transthoracic Doppler cardiac ultrasound is one of the most commonly used noninvasive means for the diagnosis of pulmonary circulatory hypertension, but its value in the diagnosis of pulmonary circulatory hypertension is controversial. To this end, we searched PubMed, Web of Science, and Ovid databases for literature examining the use of transthoracic Doppler cardiac ultrasound for the diagnosis of pulmonary hypertension, applied diagnostic trial meta-analysis research methods to assess the quality of the relevant literature, extracted diagnostic-related data for inclusion in this study, and used meta-analysis to quantify the diagnostic value of transthoracic Doppler cardiac ultrasound in patients with pulmonary hypertension. The diagnostic value of transthoracic Doppler cardiac ultrasound in patients with pulmonary hypertension was quantified using meta-analysis. The sensitivity of transthoracic Doppler cardiac ultrasound in the diagnosis of pulmonary hypertension is moderate, but its specificity is not sufficient. It can be used as a primary screening test for the diagnosis of pulmonary hypertension, but the final diagnosis is dependent on right heart float catheterization.