Boils on the buttocks are mainly caused by bacterial infections such as Staphylococcus aureus and Streptococcus haemolyticus, and the medication is usually as follows: 1) anti-inflammatory and antibacterial treatment, you can take minocycline hydrochloride capsules or doxycycline capsules or choose to apply roxithromycin capsules or azithromycin dry mix suspension; 2) herbal treatment, you can choose Baixian Xia Ta Zhe capsules or Shuang Huang Lian oral solution or Er Ding capsules, which have detoxification, fire lowering, blood cooling and pain relieving effects; 3) oral immunomodulatory drugs that improve the body’s immune system and strengthen antibacterial ability, such as splenectin lyophilized powder, transfer factor oral solution or pidomod oral solution, etc.