Q: In patients with large aneurysms (about 5*7,4*7) of bilateral posterior communicating arteries with subarachnoid hemorrhage, is craniotomy clamping or interventional embolization most appropriate? What are the criteria or recommendations of the national and international guidelines for the diagnosis and treatment of large intracranial aneurysms with multiple aneurysms? Thank you! Huang Qinghai, Department of Neurosurgery, Shanghai Changhai Hospital A: This is a very realistic and clinically common problem. The size of the aneurysm you provided should be in millimeters, right? From the size of the aneurysm, this should be a small aneurysm, and in the hands of an experienced surgeon, either craniotomy clamping or interventional embolization would be appropriate. There seems to be no more guidelines for the treatment of intracranial multiple aneurysms, but there is also a consensus that multiple aneurysms have a higher risk of rupture and bleeding and that more aggressive interventions are recommended.