Premature ejaculation manifested by short ejaculation latency time and poor ejaculation control can be treated with medications such as dapoxetine and lidocaine cream and can also be supplemented with psycho-behavioral therapy. Premature ejaculation manifested by short vaginal ejaculation latency and inability to delay ejaculation can have negative physical and psychological effects on the patient such as anxiety and avoidance of sex. Premature ejaculation can be treated with oral 5-hydroxytryptamine reuptake inhibitors such as dapoxetine and paroxetine, or sildenafil and tadalafil if combined with erectile dysfunction. Local use of anesthetics such as lidocaine cream can also help improve ejaculation control. The above medications should be applied under medical supervision. In addition, besides medication, if premature ejaculation leads to psychological and interpersonal anxiety, it can also be combined with psycho-behavioral therapy. Specific treatment can be consulted with professional medical advice.