Myocardial densification insufficiency is generally not self-curable because it is a lifelong disease and presents with progressive heart failure, malignant arrhythmia and thromboembolism. 1. Progressive heart failure: lesions involving the left ventricle can lead to ventricular systolic and diastolic insufficiency, resulting in progressive heart failure. 2. Malignant arrhythmias: These include supraventricular tachycardia, rapid paroxysmal or persistent atrial fibrillation, and paroxysmal ventricular tachycardia. The appearance of the current arrhythmia will cause the patient to have chest tightness, dyspnea, and loss of consciousness. 3. Thromboembolism: Thromboembolism may lead to dysfunction of heart, brain and other vital organs. Most of the myocardial densification insufficiency cannot be cured on its own, and there is no complete cure at present. Standardized treatment should be followed to slow down the progression of the disease.