Cough with yellow pus sputum, sore throat is most common for acute respiratory tract infections, oral amoxicillin, erythromycin and other anti-infective drugs, aminobromine and other phlegm drugs, as well as symptomatic drugs, etc. Treatment: the most common cause of acute respiratory tract infections is coughing up yellow pus sputum, sore throat. 1. Anti-infective treatment: coughing with yellow pus sputum suggests a combination of bacterial infection, oral amoxicillin, erythromycin, levofloxacin tablets, cefixime dispersible tablets and other anti-infective treatment. 2. Phlegm treatment: oral aminobromine oral solution, carbocysteine, eucalyptus-pinocampus enteric capsule and other phlegm treatment, but also nebulized budesonide anti-inflammatory, acetylcysteine solution to reduce phlegm. 3. Symptomatic treatment: Sore throat can be taken orally Ganlangbingmei tablets, Pudilan oral solution, Scutellaria baicalensis oral solution and other symptomatic improvement of symptoms. Cough with yellow pus sputum sore throat, it is recommended to consult a doctor in a timely manner, under the guidance of a specialist physician to improve the chest CT, blood tests and other targeted treatment.