What is endometrial atypical hyperplasia?

  Endometrial atypical hyperplasia is a precancerous lesion of the endometrium and is classified into simple and complex atypical hyperplasia. It can develop into endometrial cancer if left untreated, mostly due to long-term stimulation of endometrium by estrogen.  How to treat endometrial atypical hyperplasia in women of childbearing age?  1.People with fertility requirements: Hysteroscopic partial endometrial resection should be performed first, followed by postoperative adjuvant medication (high potency progesterone or GnRHa) for 3 to 6 months, and pregnancy promotion or assisted reproduction after normalization of the endometrium.  2, no fertility requirements: young people requiring preservation of fertility: hysteroscopic partial hysterectomy, postoperative adjuvant drug therapy (high potency progesterone or GnRHa), followed by etiological treatment after normalization of the endometrium.  For those who want to preserve the uterus but not the reproductive function: hysteroscopic endometrial resection with postoperative adjuvant medication (high potency progesterone or GnRHa) is feasible, and etiologic treatment will be performed after the endometrium is normal.  How to treat endometrial atypical hyperplasia in perimenopausal or postmenopausal women?  1.No fertility requirement: total hysterectomy is recommended to prevent the development of endometrial cancer.  2. Combined with serious medical diseases: for those who cannot tolerate hysterectomy, hysteroscopic endometrial resection is feasible, with close postoperative follow-up.  Since, the treatment of endometrial atypical hyperplasia varies depending on the patient’s requirements such as age, fertility requirements and preservation of the uterus, the treatment means also vary.