Because bladder irrigation chemotherapy can be irritating, patients need to be in relatively good health. If the bladder is originally damaged, or if there is a urinary tract infection, neither is suitable for bladder perfusion and treatment needs to be postponed. Patients with systemic infectious diseases such as fever and pneumonia, if chemotherapy drugs are instilled, the symptoms of the infection are likely to worsen, so instillation needs to be done after the disease has improved; if a patient develops a more serious urinary tract infection or systemic fever during instillation therapy, instillation therapy also needs to be stopped until the infection is controlled. How is infection detected? Before each perfusion treatment, patients need to check the urine routine. If the red blood cells and white blood cells in the urine are too high, it means that the patient’s urinary tract inflammation and infection are not well controlled, so it is necessary to postpone the perfusion. In addition, for patients who have just undergone cystoscopy, since cystoscopy may cause some damage to the urinary tract, the time of irrigation treatment should not be too close to the time of cystoscopy (for example, one week or less) to avoid stimulating the wound; conversely, since irrigation may cause internal bladder congestion and redness, which affects observation, patients who have just undergone irrigation are also not suitable for cystoscopy. Cystoscopy is generally recommended after two weeks. Perfusion therapy is an important tool to prevent recurrence of bladder cancer, so it is important to resume perfusion as soon as possible after recovery from these uncomfortable symptoms.