Many people have not heard of smoker’s disease. Smoker’s disease is a rare disease of the vascular network of the cerebral base that is characterized by chronic progressive narrowing or occlusion of the major bilateral branches of the cerebral arterial ring (the siphon of the internal carotid artery and the anterior and middle cerebral arteries, and sometimes the beginning of the posterior cerebral artery), followed by the development of a network of small abnormal side branches. It is named “smog” because of the many smoke-like vascular shadows that appear on cerebral angiography. So, can such a rare form of smog be treated medically now? From the moment it was discovered in the 1960s, experts have not given up exploring and researching treatments for smog. The most common reactions to smog are cerebral hemorrhage, cerebral ischemia and epilepsy, and many hospitals are currently taking conservative treatment. Therefore, smog is now medically treatable, and surgery can greatly reduce the risk of cerebral hemorrhage and ischemia caused by smog. The premise is to choose an effective surgical procedure for treatment, and a large number of clinical studies have shown that combined vascular bypass is an effective procedure for treating smog, which has achieved good results.