Chest tightness, nausea and vomiting are mainly considered to be caused by gastroenteritis, gastrointestinal tumors, heart diseases and other factors. 1. Gastroenteritis: it is mostly related to patients eating unclean and indigestible food, at this time, patients will have abdominal pain, diarrhea, nausea, vomiting and other discomforts. 2. Tumor of digestive tract: when the patient has tumor of digestive tract, the tumor will cause intestinal obstruction and obstacle of food digestion, and the patient will have nausea, vomiting, chest tightness and other discomforts. 3. Heart disease: when patients have acute angina pectoris or myocardial infarction, it will lead to myocardial abnormality, which will cause chest tightness, nausea, vomiting, chest pain and other discomforts. In addition, chest tightness, nausea and vomiting may have other reasons, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.