Generally, the route of infection of Staphylococcus aureus mainly consists of two routes: exogenous and endogenous. Exogenous infection is mainly through the respiratory tract or skin and wounds, infected with exogenous Staphylococcus aureus, such infections mostly occur after the patient infected with purulent infection of the skin and redness, edema, pain, bacterial culture can be isolated from Staphylococcus aureus. At the same time, patients should pay attention to the drug sensitivity test, according to the results of the drug sensitivity test, the choice of sensitive antibiotics for further treatment. For endogenous Staphylococcus aureus infection, it is mainly due to the patient’s low immunity and poor health, the normal flora normally hidden in the patient’s pharynx, intestine and other parts of the normal flora, due to low immunity and become pathogenic flora, further multiply and cause the body parts, such as lung and intestinal Staphylococcus aureus infection. Pneumonia caused by Staphylococcus aureus infection often causes purulent infection in patients, and if a cavity is formed in the lung, pneumonia caused by Staphylococcus aureus infection needs to be actively treated with drainage and anti-inflammatory treatment. If sputum is present, sputum culture and drug sensitivity tests are required.