Sertraline hydrochloride tablets can treat premature ejaculation, but it is mainly used to treat depression. Sertraline Hydrochloride was initially used for the treatment of depression, but in the course of its use, it was found to have the effect of prolonging the latency of ejaculation, which can play a role in the treatment of premature ejaculation, and since then it has gradually begun to be used for the treatment of premature ejaculation. Sertraline hydrochloride tablets after taking the common adverse reactions are nausea, anorexia, diarrhea, headache, etc. Rare adverse reactions are allergic rash and hypogonadism, sudden discontinuation of the drug may be insomnia, anxiety, nausea, sweating, tremor, dizziness or sensory abnormalities, etc., therefore, the dose should be gradually reduced before stopping the drug. Patients with severe heart disease should be cautious, and those with hepatic or renal insufficiency should be cautious or reduce the dosage; it is not advisable to drive vehicles, operate machinery or work at heights during the period of medication. If the patient is not feeling well, he should consult the doctor in time and take the medicine as prescribed by the doctor, and must not be negligent or take the medicine blindly on his own, so as to avoid delaying the condition.