The common causes of frequent cramps in the hands and feet are as follows: 1, calcium deficiency: calcium ions can inhibit the excitability of the neuromuscular junction, increased excitability of the neuromuscular junction when calcium deficiency, often causing twitching of the hands and feet, adults can manifest as cramps and spasmodic pain in the stomach of the calf, often occurring at night; 2, vascular diseases: for example, lower limb occlusive vasculitis can cause restricted blood supply to the lower limbs, patients often have foot Cold pain, spasm and cramping performance. Patients with deep vein thrombosis or varicose veins in the lower extremities often show obstruction of venous return, which can lead to swelling and pain in the hands, sometimes accompanied by cramping sensation.