She could not brush her teeth or wash her face, so she went to a hospital and had the two most painful teeth extracted. After taking carbamazepine, her symptoms were relieved, but in recent years, the pain gradually worsened and could not be significantly relieved by increasing the dosage of medication, so she went to the pain department of the hospital and underwent a minimally invasive surgery of radiofrequency destruction of the trigeminal nerve via the foramen ovale under 64-row CT. She woke up with a long-awaited smile. Most patients need to take carbamazepine to relieve their symptoms, but as time passes, many patients’ pain gradually worsens and they need more and more medication. There are several major side effects of the drug carbamazepine that must be noted: firstly, it can cause bone marrow suppression, inhibit the body’s hematopoietic function, causing a decrease in white blood cells, red blood cells and platelets; secondly, it can lead to liver function damage, according to statistics, long-term use of patients with liver function abnormalities of 5% to 19%, so be sure to regularly check the blood image and liver function; moreover, carbamazepine can cause drug rash, eye tremor, slurred speech, dyskinesia, drowsiness, and blurred consciousness. Despite so many side effects of the drug, many patients still have to rely on the drug to relieve their symptoms because traditional open microvascular decompression surgery is risky and even more intolerable for older patients. The pain department of Wuhan Central Hospital currently performs percutaneous puncture trigeminal nerve radiofrequency destruction surgery, which can use 64-row CT for accurate positioning and intraoperative three-dimensional reconstruction to accurately puncture a thin puncture needle into the intracranial trigeminal ganglion for thermal coagulation and destruction, which greatly improves the success rate and long-term results of this minimally invasive surgery, and the patient’s operation time is also shortened and safety is greatly improved. Within one month, seven minimally invasive surgeries were performed, with an average age of 70.2 years, and even some patients from overseas such as Xiaogan came here by name. Due to the small damage, the patients could be discharged after three days of postoperative anti-inflammatory injection, and were free from the long years of pain and drugs.