1.Can I get pregnant with hypothyroidism? For women with hypothyroidism who are taking oral thyroxine replacement therapy and want to get pregnant, they should visit the endocrinology department before getting pregnant and adjust the thyroxine (eugenol) dose for women with hypothyroidism to control TSH below 2.5. Moreover, once the patient stops menstruating or has a positive home pregnancy test, the thyroid replacement dose should be increased by 25%-30%. 2. What should I do if hypothyroidism is found during a pregnancy test? It must be emphasized that pregnant women with a clear diagnosis of hypothyroidism (including subclinical hypothyroidism) should start thyroid hormone supplementation as soon as possible from the first to the sixth week of pregnancy. The dose needs to be adjusted frequently, so the medication continues to be checked monthly for thyroid function, especially TSH, during the first six months of pregnancy. 3. What is the level of TSH control in patients with hypothyroidism in pregnancy? The guidelines recommend the following levels of TSH control during pregnancy: Early pregnancy: below 2.5,between 0.1-2.5; Mid pregnancy: 0.2-3.0; Late pregnancy: 0.3-3.0. Whenever TSH exceeds 2.5 during pregnancy, T4 levels should be checked to determine whether it is overt or subclinical hypothyroidism. If T4 is decreased, the diagnosis is overt hypothyroidism, which may have an impact on embryonic neurological development and must be treated aggressively. If TSH is elevated and T4 is normal, the diagnosis is subclinical hypothyroidism. In this case, further tests for thyroid peroxidase antibodies and thyroglobulin antibodies are required, and women with positive antibodies need more aggressive treatment. The effect of subclinical hypothyroidism on the development of the embryo is not clear. 4.How should I take medication for hypothyroidism during pregnancy? Only levothyroxine should be taken during pregnancy, no other thyroxine medications such as dry thyroxine tablets or T3 are recommended. During pregnancy, the iodine requirement increases by about 50% and WHO recommends that all pregnant and lactating women need to consume 250ug of iodine per day.