Hypothyroidism is known as hypothyroidism, the incidence of women is significantly more than men, but there is no obvious difference between men and women in terms of general symptoms, and women only have specific manifestations in menstrual irregularities, excessive menstruation, infertility, and so on. Thyroid gland itself: it can be atrophic or enlarged, and some original patients may also have enlarged pituitary gland if not treated in time. Skin: the skin is dry and puffy with mucous edema. Dermal mucopolysaccharide infiltration and body fluid storage. Digestive system: decreased metabolism and weight gain. Poor taste perception, atrophy of the gastric mucosa, and decreased gastric acid secretion. Decreased gastrointestinal motility, constipation, and in severe cases, edema of the gastrointestinal tract. Cardiovascular system: decreased myocardial contractility, decreased cardiac output, decreased activity tolerance. In severe cases, heart failure and pericardial effusion may occur. Respiratory system: hypoventilation, sleep apnea. Hematologic system: normocytic, normochromic anemia, decreased hematocrit. Nervous system: manifested by apathy, prolonged reflexes, lethargy and drowsiness. Reproductive system: men show decreased libido. In women, menstrual disorders or heavy menstrual flow. Other endocrine system: hypopituitarism may present with hypothyroidism-primary hypoadrenalism (Schmidt syndrome). Therefore, although there are significantly more women than men with hypothyroidism, there is not much variability when it comes to symptoms, which are spread all over the body, and usually require auxiliary tests to confirm the diagnosis.