Drinking alcohol is not recommended for a short period of time after taking cold medication, and patients can usually drink in small amounts 3-5 days after stopping the medication. Since most cold medications contain acetaminophen, and the risk of liver damage is significantly increased by the simultaneous application of alcohol and acetaminophen, strict abstinence from alcohol is required while taking the medication. Drinking alcohol during a cold may lower your resistance and worsen your cold symptoms. It is recommended to abstain from alcohol and smoking, avoid spicy and stimulating foods, eat a light diet, drink plenty of water, and take rest during the cold. In addition, avoid taking cold medicine or cephalosporins within 24 hours of drinking alcohol to avoid adverse reactions and aggravation of the disease.