The ancients said that food and sex are the two most basic things for human survival, and a harmonious sex life is important for promoting human psychological and physical health, for harmonious family relations, and for social relations. And premature ejaculation (PE) is the most common sexual dysfunction in men, about 25% to 40% of men at some point in their lives will occur premature ejaculation. PE can directly damage the self-esteem of men, affect the relationship between husband and wife and the stability and harmony of the family, so it is increasingly concerned. The diagnosis of premature ejaculation is mainly based on the patient’s statement of medical history, and detailed medical history inquiry is fundamental to the diagnosis and treatment of premature ejaculation. Any patient with rapid ejaculation should have a detailed medical history. The medical history of premature ejaculation can be simply divided into two types: primary premature ejaculation and secondary premature ejaculation. In patients with premature ejaculation, when physical and laboratory examinations are performed, the findings are usually normal. Nevertheless, a simple external genital examination is necessary. If a patient has erectile dysfunction in addition to premature ejaculation, necessary auxiliary examinations such as sex hormone examination, neuromyography and penile vascular examination should be performed according to organic erectile dysfunction in order to find the exact cause of erectile dysfunction and to provide targeted treatment. In many patients with premature ejaculation and erectile dysfunction coexisting, once erectile dysfunction is effectively treated, the patient’s confidence and ability to maintain erection will be enhanced and the problem of premature ejaculation will be solved.